Drug Interactions With Famciclovir

Taking certain medications together can possibly lead to dangerous drug interactions. With famciclovir, drug interactions may potentially occur if you take the medicine with digoxin or probenecid. These famciclovir drug interactions can increase the levels of digoxin or famciclovir in your blood, which can increase your risk of developing side effects.

 

An Overview of Famciclovir Drug Interactions

Famciclovir (Famvir®) can potentially interact with certain other medications. Some of these medicines that may lead to famciclovir drug interactions include:
 
  • Digoxin (Digitek®, Lanoxin®)
  • Probenecid (Benuryl®, Benemid®, Colbenemid®).
     

Famciclovir Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when famciclovir is combined with any of the drugs listed above.
 
Digoxin (Digitek, Lanoxin)
Famciclovir may slightly raise the level of digoxin in your blood, perhaps increasing your risk of digoxin side effects. However, this interaction is not likely to cause any problems for most people.
 
Probenecid (Benuryl, Benemid, ColBenemid)
Probenecid can raise the level of famciclovir in your blood, increasing your risk of famciclovir side effects. If you are taking these drugs together, your healthcare provider may need to decrease your famciclovir dosage.
 

Final Thoughts on Famciclovir Drug Interactions

It is possible that not all famciclovir drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with famciclovir that may apply to you.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;