Drug Interactions With Gabapentin (Cont.)

 
Hydrocodone
Taking gabapentin with hydrocodone can decrease the level of hydrocodone and increase the level of gabapentin in your blood. Also, taking these medications together could increase your risk of certain side effects, such as dizziness or drowsiness. Talk to your healthcare provider before using these medications together.
 
Morphine
Morphine can increase the level of gabapentin in your blood, potentially increasing your risk of side effects. Talk to your healthcare provider before taking these medications together, as you may need a lower gabapentin dosage.
 
Naproxen
Naproxen seems to increase the amount of gabapentin that is absorbed into your body, possibly increasing the risk of side effects. Talk to your healthcare provider before taking these medications together.
 

Final Thoughts on Drug Interactions With Gabapentin

It is possible that not all drug interactions with gabapentin were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;