Gralise Drug Interactions
To help reduce your risk for potentially serious drug interactions with Gralise, tell your doctor about any other medications you are taking. Gralise can negatively react with products such as alcohol, certain antacids, and morphine, just to name a few. These interactions can cause the body to metabolize the medications differently than intended, possibly increasing your risk for side effects or decreasing the medications' effectiveness.
An Overview of Interactions With GraliseGralise™ (extended-release gabapentin) may react with many other medications. Some of the drugs that may lead to Gralise interactions include but are not limited to:
- Antacids containing aluminum or magnesium (such as Phillips'® Milk of Magnesia, Maalox®, or Gaviscon®)
- Hydrocodone (such as Lortab®, Norco®, Vicodin®)
- Morphine (Avinza®, MS Contin®, MSIR®, Oramorph SR®, Roxanol®)
- Naproxen (Aleve®, Anaprox®, Naprelan®, Naprosyn®).
Gralise Drug Interactions ExplainedThe following sections explain in detail the potentially negative reactions that can occur when Gralise is combined with any of the drugs listed above.
Alcohol can increase your risk for certain Gralise side effects, such as drowsiness or dizziness. Talk to your healthcare provider about drinking alcohol while taking Gralise.
Aluminum or Magnesium Antacids
Antacids that contain aluminum or magnesium can decrease the absorption of Gralise into your bloodstream, perhaps making it less effective. In order to avoid this interaction, do not take these medications within two hours of each other.