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Gralise Uses

Gralise is approved to treat postherpetic neuralgia, which is nerve pain that can occur after a case of shingles. It is approved for people over the age of 18. Although it is not exactly known how this drug works, it is thought to bind to certain receptors in the central nervous system. Possible off-label uses for Gralise may include treating epilepsy, bipolar disorder, and migraines.

What Is Gralise Used For?

Gralise™ (extended-release gabapentin) is a prescription medication used to treat postherpetic neuralgia (nerve pain that occurs after a case of shingles).
 
About one million people develop shingles each year, and a number of them experience a complication called postherpetic neuralgia. This is pain that is present in the affected area for months, or even years, after the shingles rash has healed. The most bothersome symptom of postherpetic neuralgia is pain. The pain can result in an inability to perform daily tasks of living and may be described as:
 
  • Agonizing
  • Excruciating
  • Burning
  • Sharp, electric-like jabs
  • Throbbing
  • Aching.
 
Postherpetic neuralgia treatment usually involves medication. Gralise is one of the medications approved to treat the pain associated with postherpetic neuralgia.
 
Notably, Gralise is not approved to treat epilepsy (another gabapentin medication, Neurontin®, is approved for epilepsy treatment).
 

How Does Gralise Work?

It is not known exactly how this medication works to treat nerve pain. Preliminary research suggests that Gralise binds to certain parts of calcium channels in the central nervous system, which may be how this medicine helps relieve nerve pain.
 

Can Children Use Gralise?

Gralise is not approved for use in children (usually defined as people younger than 18 years of age). The drug's safety and effectiveness have not been studied in this age group. This makes sense, as postherpetic neuralgia usually occurs in older adults rather than children.
 
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Gralise Medication Information

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