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Gralise Warnings and Precautions

A few of the conditions you should let your doctor know about before taking Gralise include depression, cancer, or kidney disease. Other warnings and precautions for Gralise relate to things such as a potential risk for vision problems and the safety of using the medicine if you are pregnant or breastfeeding. Also, do not suddenly stop taking Gralise; it may increase your risk for seizures.

What Should I Tell My Healthcare Provider?

Talk with your healthcare provider prior to taking Gralise™ (extended-release gabapentin) if you have:
 
  • Depression
  • A history of suicidal thoughts or actions
  • Kidney disease, such as kidney failure (renal failure)
  • Cancer
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Gralise

Some warnings and precautions to be aware of prior to taking this drug include the following:
 
  • Do not stop taking Gralise suddenly. If you need to stop taking this medication, your healthcare provider will advise you about how to gradually reduce the dosage over a period of at least one week. Presumably, this is because stopping seizure medications too quickly can increase your risk for seizures. Although Gralise is not approved to treat seizures, other gabapentin medications, including Neurontin®, are approved for seizure treatment.
 
  • Gralise increases the risk for certain cancers in rats. However, it is not known if this medicine increases the risk for cancer in humans.
 
  • Make sure to see how Gralise affects you before driving or operating any machinery, as this drug can cause drowsiness and dizziness. In general, you should avoid drinking alcohol while taking Gralise, as it may increase your risk for drowsiness and other problems.
 
  • Gralise can cause vision problems, especially blurred vision or double vision. Let your healthcare provider know if you experience any vision problems while taking this drug.
 
  • Let your healthcare provider know if you have kidney disease, as you may need a lower Gralise dosage.
 
 
  • Gralise is a pregnancy Category C medication. This means that it may not be safe for pregnant women, although the full risks are unknown. Talk to your healthcare provider about the risks and benefits of taking the drug during pregnancy (see Gralise and Pregnancy).
 
  • Gralise passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Gralise and Breastfeeding).
 
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Gralise Medication Information

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