Shingles Home > Gralise

Gralise is a prescription drug used to treat postherpetic neuralgia, which is nerve pain that occurs after having a case of shingles. It comes in the form of a tablet that is taken once a day with the evening meal. Dizziness, drowsiness, and headaches are some of the most common side effects of this medication.

What Is Gralise?

Gralise™ (extended-release gabapentin) is a prescription medication approved for the treatment of nerve pain that occurs after a case of shingles (known medically as postherpetic neuralgia). It is a long-acting tablet that is taken just once a day.
(Click Gralise Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Gralise is made by Abbott Laboratories.

How Does Gralise Work?

It is not known exactly how this medication works to treat nerve pain. Preliminary research suggests that Gralise binds to certain parts of calcium channels in the central nervous system, which may be how the medicine works to relieve nerve pain.

When and How to Take It

Some general considerations to keep in mind during treatment with this medication include the following:
  • Gralise comes in tablet form. It is usually taken by mouth once a day with the evening meal. It is important to take this drug with food.
  • You must swallow the tablets whole; do not chew, crush, or dissolve them, as this causes the medication to be released too quickly.
  • For this medication to work properly, it must be taken as prescribed.

Dosing Information

The dosage your healthcare provider recommends will vary, depending mostly on how well your kidneys are functioning.
(Click Gralise Dosage for more information.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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